The checkpoint is planned from 10:00 p.m. tonight until 3 a.m. Saturday morning at 900 Missouri Avenue North by Babcock Furniture.
Law enforcement officers including a K-9 unit will look for alcohol and drug impaired drivers. The goal is to reduce DUI related injuries, according to a news release.
Deputies and officers will also check for driver license, registration and equipment violations.
The Pinellas County Sheriff's Office Mobile Command bus will be on site for breath testing and the processing of arrested individuals.